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Wass Group - Computational Biology |
Publications |
View Dr Mark Wass's publications on Google Scholar or PubMed Each title below links to the journal page for the publication and altmetric data shown on the left. |
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Is the Bombali virus pathogenic in humans? Martell HJ, Masterson MG, McGreig JE, Michaelis M, Wass MN, Bioinformatics in press. | |
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A QTL for Number of Teats Shows Breed Specific Effects on Number of Vertebrae in Pigs: Bridging the Gap Between Molecular and Quantitative Genetics van Son M,..., Wass MN et al.,, Frontiers in Genetics 10:272. | |
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Understanding of researcher behaviour is required to improve data reliability Wass MN, Ray L, Michaelis M, Gigascience In press. | |
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Herd Immunity to Ebolaviruses Is Not a Realistic Target for Current Vaccination Strategies Masterson SG, Lobel L, Carroll MW, Wass MN, Michaelis M, Frontiers in Immunology 9:1025. | |
| Changes associated with Ebola virus adaptation to novel species Pappalardo M et al., Wass MN, Bioinformatics 33:1911-1915. | |
| Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS Saintas E et al., Wass MN, Michaelis M, PLOS One 12 e0172140 | |
| Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance Voges Y, Michaelis M, et al., Wass MN, Rodel F, Cinatl J., Cell Death and Disease 7, e2410 | |
| Risks Posed by Reston, the Forgotten Ebolavirus D Cantoni, A Hamlet, M Michaelis, MN Wass, JS Rossman, mSphere 1 (6), e00322-16 | |
| An expanded evaluation of protein function prediction methods shows an improvement in accuracy Jiang et al., Genome Biology 2016 | |
| Computational analysis of Ebolavirus data: prospects, promises and challenges Michaelis M, Rossman JS, Wass MN Biochem Soc Trans (2016) 44:973-978 | |
| Desulfovibrio vulgaris CbiKP cobaltochelatase: Evolution of a haem binding protein orchestrated by the incorporation of two histidine residues Susana A.L. Lobo, Marco A.M. Videira, Isabel Pacheco, Mark N. Wass, Martin J. Warren, Miguel Teixeira, Pedro M. Matias, Celia V. Romao, Ligia M. Saraiva | |
| Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses Pappalardo M, Julia M, Howard M, Rossman JS, Michaelis M, Wass MN | |
| Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport Michaelis M, Rothweiler F, Wurglics M, Aniceto N, Dittrich M, Zettl H, Wiese M, Wass M, Ghafourian T, Schubert-Zsilavecz M, Cinatl J.(2016) Oncotarget,In press doi: 10.18632/oncotarget.7345 | |
| The Role of Protein Modelling in Predicting the Disease Severity of Cystinuria Wong KA, Wass M, Thomas K (2015) European Urology, 69, 543-4. | |
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The Phyre2 web portal for protein modeling, prediction and analysis Kelley LA, Mezulis S1, Yates CM, Wass MN , Sternberg MJ.(2015) Nature Protocols, 10, 845-58 | |
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Ten simple rules for a community computational challenge Friedberg I, Wass MN, Mooney SD, Radivojac P., Thomas K (2015) PLOS Comp Bio, 11, e1004150. | |
| Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen Michaelis M, Agha B, Rothweiler F, Löschmann N, Voges Y, Mittelbronn M, Starzetz T, Harter PN, Abhari BA, Fulda S, Westermann F, Riecken K, Spek S, Langer K, Wiese M, Dirks WG, Zehner R, Cinatl J, Wass MN , Cinatl J Jr.(2015) Sci Rep, 5, 8202 | |
| Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility Talman AM, Prieto JH, Marques S, Ubaida-Mohien C, Lawniczak M, Wass MN, Xu T, Frank R, Ecker A, Stanway RS, Krishna S, Sternberg MJ, Christophides GK, Graham DR, Dinglasan RR, Yates JR 3rd, Sinden RE. (2015) Malar J. 2014, 13, 315. | |
| The South Asian genome Chambers JC, Abbott J, Zhang W, Turro E, Scott WR, Tan ST, Afzal U, Afaq S, Loh M, Lehne B, O'Reilly P, Gaulton KJ, Pearson RD, Li X, Lavery A, Vandrovcova J, Wass MN , Miller K, Sehmi J, Oozageer L, Kooner IK, Al-Hussaini A, Mills R, Grewal J, Panoulas V, Lewin AM, Northwood K, Wander GS, Geoghegan F, Li Y, Wang J, Aitman TJ, McCarthy MI, Scott J, Butcher S, Elliott P, Kooner JS (2014) PLOS One, 9, e102645 | |
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The genetic diversity of cystinuria in a UK population of patients Wong KA, Mein R, Wass M, Flinter F, Pardy C, Bultitude M, Thomas K (2015) BJU Int, 116, 109-16. | |
| VarMod: modelling the functional effects of non-synonymous variants Pappalardo M, Wass MN (2014) Nucl Acids Res, 42, W331-6 | |
| The automated function prediction SIG looks back at 2013 and prepares for 2014 Wass MN, Mooney SD, Linial M, Radivojac P, Friedberg I (2014) Bioinformatics, 30, 2091-2. | |
| A large-scale evaluation of computational protein function prediction. Radivojac et al., (2013) Nature Methods,10, 221-227 | |
| CombFunc: predicting protein function using heterogeneous data sources Wass M.N., Barton G., Sternberg M.J. et al., (2012) Nucleic Acids Research,40, W466-470. | |
| Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls. Journal of Parasitology Wass M.N., Stanway, R., Blagborough, A., Lal, K., Prieto, J.H., Raine, D., Sternberg, M.J., Talman, A.M., Tomley F., Yates III, J., Sinden, R.E. (2012) Parasitology, 139, 1131-1145. | |
| Protein-protein interaction sites are hot spots for disease-associated non-synonymous SNPs David, A., Razali, R., Wass, M.N.*, Sternberg, M.J.E.* (2011) . Human Mutation,33, 359–363. *Joint senior author | |
| Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma Chambers JC, Zhang W, Sehmi J, Li X, Wass M.N.* et al., (2011) Nat Genet. doi: 10.1038/ng.970 *Co first author | |
| Challenges for the prediction of macromolecular interactions Wass M.N., David A., Sternberg M.J. (2011) . Curr Op Struct Biol. 21:382-90 | |
| Towards the prediction of interaction partners using Physical docking Wass M.N., Fuentes G., Pons, C., Pazos F., Valencia A. (2011) . Mol Syst Biol 7:469 | |
| The flagellum in malarial parasites Sinden R.E., Talman A., Marques S.R., Wass M.N., Sternberg M.J. (2010). Curr Opin Microbiol. 13:491-500 | |
| 3DLigandSite: predicting ligand-binding sites using similar structures Wass M.N, Kelley L.A. and Sternberg M.J. (2010). NAR 38, W469-73 | |
| Genetic loci influencing kidney function and chronic kidney disease Chambers J.C. et al., (2010) . Nat Genet 42:373-5 | |
| Genetic variation in SCN10A influences cardiac conduction Chambers, J.C. et al., (2010) Nat Genet, 42:149-52 | |
| Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels Chambers, J.C., Zhang, W., Li, Y., Sehmi, J., Wass, M.N. et al., (2009) . Nat Genet, 41, 1170-2. | |
| Prediction of ligand binding sites using homologous structures and conservation at CASP8 Wass, M.N. and Sternberg, M.J. (2009). Proteins, 77 Suppl 9:147-51. | |
| ConFunc--functional annotation in the twilight zone | |
| Convergent Evolution of Enzyme Active Sites Is not a Rare Phenomenon | |
| Mitochondrial proton leak in metabolic depression:Life in Limbo.
Brand, M. D., Boutilier, R. G., Wass, M., St-Pierre, J. & Bishop, T. (2001). In Molecular Mechanisms of Metabolic Arrest edited by K. B. Storey, 59-76 | |